Pumilsan

Pumilsan may be available in the countries listed below.

Ingredient matches for Pumilsan

Dequalinium Chloride

Dequalinium Chloride is reported as an ingredient of Pumilsan in the following countries:

• Italy

International Drug Name Search

Midaflex

Midaflex may be available in the countries listed below.

Ingredient matches for Midaflex

Cefalexin

Cefalexin is reported as an ingredient of Midaflex in the following countries:

• Oman

International Drug Name Search

Remicade

In the US, Remicade (infliximab systemic) is a member of the following drug classes: antirheumatics, TNF alfa inhibitors and is used to treat Ankylosing Spondylitis, Behcet's Disease, Bullous Pemphigoid, Celiac Disease, Cogan's Syndrome, Crohn's Disease - Acute, Crohn's Disease - Maintenance, Giant Cell Arteritis, Juvenile Idiopathic Arthritis, Kawasaki Disease, Neurosarcoidosis, Pemphigoid, Pemphigus, Polychondritis, Psoriasis, Psoriatic Arthritis, Pulmonary Fibrosis, Pyoderma Gangrenosum, Rheumatoid Arthritis, SAPHO Syndrome, Sarcoidosis, Sjogren's Syndrome, Subcorneal Pustular Dermatosis, Toxic Epidermal Necrolysis, Ulcerative Colitis and Uveitis.

US matches:

• Remicade

Ingredient matches for Remicade

Infliximab

Infliximab is reported as an ingredient of Remicade in the following countries:

• Argentina


• Australia


• Austria


• Belgium


• Canada


• Chile


• China


• Colombia


• Costa Rica


• Croatia (Hrvatska)


• Czech Republic


• Denmark


• Dominican Republic


• Ecuador


• El Salvador


• Finland


• France


• Georgia


• Germany


• Greece


• Guatemala


• Honduras


• Hong Kong


• Hungary


• Iceland


• Indonesia


• Ireland


• Israel


• Italy


• Japan


• Luxembourg


• Malaysia


• Mexico


• Netherlands


• New Zealand


• Nicaragua


• Norway


• Oman


• Panama


• Peru


• Philippines


• Portugal


• Romania


• Russian Federation


• Serbia


• Singapore


• Slovakia


• Slovenia


• Spain


• Sweden


• Switzerland


• Thailand


• Tunisia


• Turkey


• United Kingdom


• United States


• Venezuela

International Drug Name Search

Sanaxin

Sanaxin may be available in the countries listed below.

Ingredient matches for Sanaxin

Cefalexin

Cefalexin is reported as an ingredient of Sanaxin in the following countries:

• Austria

International Drug Name Search

Miacalcin

Miacalcin is a brand name of calcitonin, approved by the FDA in the following formulation(s):

MIACALCIN (calcitonin salmon - injectable; injection)

• 
  Manufacturer: NOVARTIS
  
  Approval date: March 29, 1991
  
  Strength(s): 200 IU/ML ^[RLD]

MIACALCIN (calcitonin salmon - spray, metered; nasal)

• 
  Manufacturer: NOVARTIS
  
  Approval date: August 17, 1995
  
  Strength(s): 200 IU/SPRAY ^[RLD][AB]

Has a generic version of Miacalcin been approved?

A generic version of Miacalcin has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Miacalcin and have been approved by the FDA:

CALCITONIN-SALMON (calcitonin salmon spray, metered; nasal)

• 
  Manufacturer: APOTEX INC
  
  Approval date: November 17, 2008
  
  Strength(s): 200 IU/SPRAY ^[AB]


• 
  Manufacturer: PAR PHARM
  
  Approval date: June 8, 2009
  
  Strength(s): 200 IU/SPRAY ^[AB]

Note: No generic formulation of the following product is available.

• calcitonin salmon - injectable; injection

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Miacalcin. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.

Related Patents

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

• 
  Galenic compositions comprising calcitonin and their use
  Patent 5,733,569
  Issued: March 31, 1998
  Inventor(s): Azria; Moise & Cavanak; Thomas
  Assignee(s): Novartis Corporation
  Pharmaceutical compositions for nasal administration comprising i) a calcitonin, and ii) benzalkonium chloride, and/or iv) a surfactant, suitable for application to the nasal mucosa, in iii) a liquid diluent or carrier, suitable for application to the nasal mucosa. The compositions are suitably adapted for administration in the form of a nasal spray.
  
  Patent expiration dates:
  
  
  • March 31, 2015
    
    ✓ 
    Patent use: NASAL ADMINISTRATION
  
  



• 
  Galenic compositions comprising calcitonin and their use
  Patent 5,759,565
  Issued: June 2, 1998
  Inventor(s): Azria; Moise & Cavanak; Thomas
  Assignee(s): Novartis Corporation
  Pharmaceutical compositions for nasal administration comprising i) a calcitonin, and ii) benzalkonium chloride, and/or iv) a surfactant, suitable for application to the nasal mucosa, in iii) a liquid diluent or carrier, suitable for application to the nasal mucosa. The compositions are suitably adapted for administration in the form of a nasal spray.
  
  Patent expiration dates:
  
  
  • March 31, 2015
    
  
  

See also...

• Miacalcin Consumer Information (Drugs.com)
• Miacalcin Consumer Information (Wolters Kluwer)
• Miacalcin Spray Consumer Information (Wolters Kluwer)
• Miacalcin Consumer Information (Cerner Multum)
• Miacalcin Injection Advanced Consumer Information (Micromedex)
• Miacalcin Nasal Advanced Consumer Information (Micromedex)
• Miacalcin Parenteral Advanced Consumer Information (Micromedex)
• Calcitonin Salmon Spray Consumer Information (Wolters Kluwer)
• Calcitonin-Salmon Consumer Information (Wolters Kluwer)
• Calcitonin injection Consumer Information (Cerner Multum)
• Calcitonin nasal Consumer Information (Cerner Multum)
• Calcitonin (salmon) Nasal Advanced Consumer Information (Micromedex)
• Calcitonin Injection Advanced Consumer Information (Micromedex)
• Calcitonin Nasal Advanced Consumer Information (Micromedex)
• Calcitonin Parenteral Advanced Consumer Information (Micromedex)
• Calcitonin AHFS DI Monographs (ASHP)

Busulfex

Generic Name: busulfan (Intravenous route)

bue-SUL-fan

Intravenous route(Solution)

Busulfan injection is a potent cytotoxic drug that causes profound myelosuppression at the recommended dosage. It should be administered under the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic drugs and the management patients with severe pancytopenia. Appropriate management of therapy and complications is only possible when adequate diagnostic and treatment facilities are readily available .

Commonly used brand name(s)

In the U.S.

• Busulfex

Available Dosage Forms:

• Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Alkylating Agent

Uses For Busulfex

Busulfan belongs to the group of medicines known as alkylating agents. It is used to treat some kinds of cancer of the blood. It may also be used as a conditioning regimen prior to progenitor cell transplantation for treatment of chronic myelogenous leukemia.

Busulfan seems to act by interfering with the function of the bone marrow. Since the growth of normal body cells may also be affected by busulfan, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with busulfan, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

Busulfan is available only with your doctor's prescription.

Before Using Busulfex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of busulfan in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of busulfan in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Metronidazole


• Mumps Virus Vaccine, Live


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Typhoid Vaccine


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Itraconazole


• Ketobemidone


• Phenytoin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Chickenpox (including recent exposure) or


• Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body

• Gout (history of) or


• Kidney stones (or history of)—Busulfan may increase levels of uric acid in the body, which can cause gout or kidney stones

• Head injury or


• Convulsions (seizures, history of)—Busulfan injection and very high doses of oral busulfan can cause convulsions (seizures)

• Infection—Busulfan may decrease your body's ability to fight infection


• Thalassemia—Busulfan may cause increased pressure within the heart in children

Proper Use of Busulfex

Take this medicine only as directed by your doctor. Do not take more or less of it, and do not take it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.

Take each dose at the same time each day to make sure it has the best effect.

While you are taking this medicine, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.

This medicine sometimes causes nausea and vomiting. However, it is very important that you continue to use the medicine, even if you begin to feel ill. Do not stop taking this medicine without first checking with your doctor. Ask your health care professional for ways to lessen these effects.

If you vomit shortly after taking a dose of busulfan, check with your doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

Handle and dispose of this medicine with care as directed by your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Busulfex

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

While you are being treated with busulfan, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Busulfan may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have taken oral polio vaccine within the last several months. Do not get close to them, and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Busulfan can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some body tissue studies may be affected by this medicine.

Busulfex Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Black, tarry stools


• blood in urine or stools


• cough or hoarseness


• fever or chills


• inflammation of the mouth


• lower back or side pain


• painful or difficult urination


• pinpoint red spots on skin


• unusual bleeding or bruising

Less common

• Chest pain


• dizziness


• fast or irregular breathing


• joint pain


• light-headedness


• puffiness or swelling around face


• rapid heartbeat


• shortness of breath


• sudden, severe decrease in blood pressure


• sweating


• swelling of fingers, hands, arms, lower legs, or feet


• sweating


• tingling in lower legs, hands, or feet

Rare

• Blurred vision


• difficulty swallowing


• heartburn


• severe upper abdominal and back pain


• vomiting blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Abdominal pain


• anxiety


• diarrhea


• general fatigue or muscle pain


• headache


• missed or irregular menstrual periods


• loss of appetite


• nausea and vomiting


• rash


• trouble in sleeping


• weight loss (sudden)

Less common

• Bloody nose


• confusion


• constipation


• darkening of skin


• depression


• dry mouth


• inflammation at place of injection


• itching


• sore throat or cough


• stuffy nose, runny nose, or sneezing

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Black, tarry stools


• blood in urine or stools


• cough or hoarseness, accompanied by fever or chills


• fever or chills


• lower back or side pain, accompanied by fever or chills


• painful or difficult urination, accompanied by fever or chills


• pinpoint red spots on skin


• shortness of breath


• unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Busulfex side effects (in more detail)

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More Busulfex resources

• Busulfex Side Effects (in more detail)
• Busulfex Use in Pregnancy & Breastfeeding
• Busulfex Drug Interactions
• Busulfex Support Group
• 0 Reviews for Busulfex - Add your own review/rating

• Busulfex Prescribing Information (FDA)


• Busulfex MedFacts Consumer Leaflet (Wolters Kluwer)


• Busulfex Concise Consumer Information (Cerner Multum)


• Busulfan Monograph (AHFS DI)


• Busulfan Professional Patient Advice (Wolters Kluwer)


• Myleran Prescribing Information (FDA)


• Myleran MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Busulfex with other medications

• Bone Marrow Transplantation
• Chronic Myelogenous Leukemia
• Thrombocythemia

Septacin

Septacin may be available in the countries listed below.

Ingredient matches for Septacin

Ambroxol

Ambroxol hydrochloride (a derivative of Ambroxol) is reported as an ingredient of Septacin in the following countries:

• Mexico

International Drug Name Search